MMP12 and pancreatic neoplasm: Expression of genes [MMP1, MMP3, MMP12, MMP19, TIMP1, ITGB3, FN1, interleukin 27 receptor subunit alpha (IL27RA) and transforming growth factor beta receptor 1 (TGFBR1)] from these pathways, which are known to be upregulated in human PDAC (Slapak et al., 2020; Zhai et al., 2016; Zhu et al., 2019; Ligorio et al., 2019; Chen et al., 2019), was found to be overexpressed in OCM pancreatic tumors (Fig. S7, heatmaps), suggesting similarities between the porcine and human pancreatic tumor microenvironment.