For example, the BRAF V600E mutation in MM-348 found at 73% VAF using the Illumina cancer panel (Table S1) was detected at 74% VAF using the Swift cancer panel, the EGFR S715I mutation in LNGCA-0002 was found at 5% in both panels, and, in the CRC-0015, the three pathogenic mutations, APC Y1376fs, KRAS G12D, TP53 T211I, were found at 32%, 63%, 56% (respectively) using the Illumina panel, and 32%, 68%, 55% using the Swift panel. The gene discussed is TP53; the disease is cancer.