In relation to this, the protein encoded from the FAF1 gene induces apoptosis by binding to the FAS antigen and acts as a tumor suppressor involved in the regulation of NF-kB signaling [16], and the INPP4B gene acts as a suppressor for invasion of prostate carcinoma PC-3 cells and oncogenic PKC signaling [17]. Here, INPP4B is linked to neoplasm.