AKT1 and cancer: The selected 1325 genes were further applied to ConsensusPathDB (CPDB) to analyze cellular signaling pathways, and seven cancer-related pathways, the focal adhesion kinase (FAK)/PI3K-Akt signaling pathway, JAK-STAT pathway, Notch signaling pathway, receptor tyrosine kinase/PDGF signaling pathway, TGF-β signaling pathway, VEGFA signaling pathway, and Wnt signaling pathway were identified with 163 genes (Table S3).