The difference in the expression of inflammation-related proteins in the brain tissue of AD mouse models after different interventions (Figure 6) showed that the relative expression of GFAP in the brain tissue of the AD mouse model in the Zun-Pre group was higher than that in the donepezil group, benfotiamine group, Zun-Int M combined benfotiamine group, and Vehicle group; the difference was statistically significant (P<0.05). This evidence concerns the gene GFAP and Alzheimer disease.