To our knowledge, this is the first indication of impaired calcium homeostasis in DBA, whereas high intracellular calcium concentration levels have been already described in lymphoblast cell lines derived from patients with Shwachman-Diamond syndrome (Ravera et al., 2016), another ribosomopathy characterized by increased stabilization of p53 (Warren, 2018). This evidence concerns the gene TP53 and Diamond-Blackfan anemia.