In our study, clinical indicators within 24 h after admission were used (i.e., APACHE IV/APSIII, maximum HCO3, minimum HCO3, maximum lactate, minimum lactate, maximum creatinine, minimum creatinine, maximum albumin, minimum albumin, maximum glucose, minimum glucose, maximum WBC, minimum WBC, and age) combined with the machine learning model to obtain an accurate prediction of sepsis-associated ARDS. This evidence concerns the gene ALB and Sepsis.