Daily dosage of the insulin was similar; however, insulin resistance indices eGDR1 and eGDR2 were significantly lower in obese T1DM patients than in non-obese T1DM patients: eGDR1: 5.16 ± 1.33 vs. 6.96 ± 1.32; eGDR2: 9.37 ± 1.21 vs. 10.66 ± 0.9 (p = 0.0001, p = 0.0001), meaning insulin resistance (Table 2). This evidence concerns the gene INS and type 1 diabetes mellitus.