The Tandem t:slim X2 insulin pump (Tandem Inc., San Diego, CA, USA) uses a Dexcom G6 sensor (Dexcom Inc., San Diego, CA, USA) and a closed loop algorithm (Control-IQTM) that automates basal insulin delivery and correction boluses, prevents and protects against hypoglycemia, and intensifies control overnight (9). This evidence concerns the gene INS and Hypoglycemia.