After adjusting for confounding variables (including age, HGB, LDL-c, TG, AST, HCT, ALT, BUN, HBA1C, FIB, ALB, previous stroke or TIA, hypertension, NIHSS score, DM, atrial fibrillation, smoking, and stroke etiology), similar results were obtained, i.e., the association between BMI and the probability of unfavorable outcomes was non-linear in men with AIS, whereas their relationship was not statistically significant in women with AIS (Table 5). The gene discussed is GPT; the disease is hypertensive disorder.