reported that small nucleolar RNA 42 (SNORA42) could inhibit DHX9 from being ubiquitinated and degraded by reducing DHX9 transports into the cytoplasm and then increased DHX9 expression activated NF-κB signaling via DHX9/p65 axis to promote ESCC proliferation and migration. The gene discussed is SNORA80E; the disease is esophageal squamous cell carcinoma.