Table 1 listed all patients and their clinical characteristics. Statistical analysis showed that the Ki-67 status was significant different between the SLN- and SLN+ groups with P<0.05. No significant difference was found between the two groups in regard to age, menstruation status, tumor location, histological grade, histological type, ER status, PR status and HER-2 status (P>0.05). This evidence concerns the gene MKI67 and neoplasm.