The coexistence of arthralgia, fatigue and insomnia after adjusting for race, chemotherapy history, nonsteroidal antiinflammatory drugs (NSAIDs), age and BMI was in connection with elevated C-reactive protein (CRP), eotaxin, monocyte chemokine-1 as well as vitamin D-binding protein (VDBP) (33). The gene discussed is CRP; the disease is insomnia.