Phosphoglycerol dehydrogenase, by binding and regulating PCBP2 [Poly(rC) binding protein 2] protein expression to promote the mRNA stability of SLC7A11 (the catalytic subunit of system Xc–), can inhibit cell ferroptosis and ultimately promote the malignant progression of bladder cancer (Shen et al., 2022). This evidence concerns the gene PCBP2 and urinary bladder cancer.