YES1 and non-small cell lung carcinoma: For example, Redin et al. have demonstrated that Yes1, a member of the SFKs, is involved in increasing the number of regulatory T-cells (Treg) which are able to infiltrate tumors in cases of non-small cell lung cancer (NSCLC), thus Yes1 being one of the most important predictors of a poor prognosis in this type of cancer.