LGALS3 and cancer: Furthermore, multiple studies have indicated that galectin-1, a homodimeric protein involved in angiogenesis (Thijssen and Griffioen 2014) and cross-linking receptors (Hernandez et al., 2006), and galectin-3, a chimaera-type protein associated with cancer metastasis (Fortuna-Costa et al., 2014) and inflammatory regulation (Henderson and Sethi 2009), are mainly involved in endometrial cancer.