Before PSM, there were statistically significant differences in sex, age, ethnicity, SAPS II, SOFA score, Charlson Comorbidity Index, respiratory rate, heart rate, SPO2, hemoglobin, BUN, Scr, albumin, anion gap, bicarbonate, sodium, potassium, chloride, PT, APTT, lactate, urine output, vasopressor use, ventilator use, RRT use, atrial fibrillation, hypertension, CAD, liver disease, renal disease, and malignancy between the two groups. This evidence concerns the gene ALB and liver disorder.