There was no correlation between cfDNA concentration and other clinical indicators in LN patients, such as neutrophilic granulocyte percentage, C-reactive protein, erythrocyte sedimentation rate, albumin, serum creatinine, estimated glomerular filtration rate, urinary red blood cells, 24-h urinary protein, complement 3 or complement 4, immunoglobin, and SLEDAI score (P > 0.05). The gene discussed is CRP; the disease is lobular neoplasia.