To determine the function of RNF7 in glioma progression, the expression of RNF7 in multiple human glioma cell lines, U‐251, U‐87MG, SHG44, T98G and HEB normal human brain glial cells was detected, and RNF7 was highly expressed in glioma cells (Figure S1D). The gene discussed is RNF7; the disease is central nervous system cancer.