VDAC1 and cancer: In cancers, VDAC1 is overexpressed [38–40], while its oligomerization and, thereby, apoptosis are prevented by the overexpression of anti-apoptotic proteins such as hexokinase and Bcl2, and their detachment from VDAC1 leads to VDAC1 oligomerization and apoptosis [22, 37, 39].