To date, NMT1, NMT2, ZDHHC2, ZDHHC3, ZDHHC6, ZDHHC8, ZDHHC9, ZDHHC12, ZDHHC13, and ZDHHC14 have been closely linked with most cancer types.275,287,350–356 The development of inhibitors targeting NMT and ZDHHC family to treat cancer is in progress. The gene discussed is ZDHHC14; the disease is cancer.