NMT1 and cancer: This in turn promotes the interaction of AMPK and the ATG16 complex and mitochondrial removal through autophagy, which helps to maintain cancer cell viability in ccRCC, lung cancer, and ovarian serous cystadenocarcinoma (OSC).243 In another two studies, researchers found that myristoylation of the lysosomal adaptor mTOR activator 1 (LAMTOR1) by NMT1 at G2 promotes its palmitoylation and anchoring to the lysosome, which increases mTOR activity to inhibit autophagy and promote the progression of lung cancer, bladder cancer, colorectal cancer, and cervical carcinoma.244,245