TNF and diabetic kidney disease: reported a new one-dimensional Cu (II) coordination polymer by using a NNO tridentate (NNO) Schiff base ligand4-fluoro-2-(((2-(methylamino)ethyl)amino)methyl)phenol, which can downregulate the serum amyloid A and TNF-α in STZ induced DKD rats (Pan-Pan Lin and Chen, 2021).