Given that RAD51 and BRCA1 are vital components in homologous recombination repair [31], we reasoned that by interacting with RAD51 and BRCA1, Wee1 may aid to initiate the DNA repair process, preventing DNA damage and enhancing the growth of CML cells. This evidence concerns the gene BRCA1 and chronic myelogenous leukemia, BCR-ABL1 positive.