HDAC8 and neoplasm: BMX (NBM-T-L-BMX-OS01), a histone deacetylase 8 inhibitor (HDAC8i), shows significant anti-cell proliferation effects in CRC cells, human umbilical endothelial cells, lung cancer cells, and glioblastoma cells, and it also exhibits tumor suppression ability in an animal xenograft model [8, 19, 20].