Here, we will illustrate how NetAct infers TF activity on two cases of microarray KD experiments—one case for shRNA KD of FOXM1 and shRNA KD of MYB in lymphoma cells (GEO: GSE17172 [51]), and another case for KD of BCL6 on both OCI-Ly7 and Pfeiffer GCB-DLBCL cell lines (GEO: GSE45838 [2]). The gene discussed is MYB; the disease is lymphoma.