PRRT2 and infantile convulsions and choreoathetosis: To elucidate the interplay between collagen type I-rich TME and iCCA progression, we first examined the gene expression profile of the integrin adhesome network24, which consists of integrins, major cell–matrix adhesion receptors, and their downstream signaling effectors on a GEO dataset, GSE76297, of Thai iCCA samples and their adjacent normal tissue counterparts (n = 91)25.