MCM8 and hepatocellular carcinoma: Meanwhile, the multivariate Cox regression analysis confirmed that Child-Pugh class B (HR (95%CI) 4.323(2.156-8.668), P <0.001), vascular invasion (HR (95%CI) 2.285(1.226-4.192), P = 0.008) and higher MCM8 protein level (HR (95%CI) 1.816(1.031-3.201), P = 0.039) were independent risk factors for OS in patients with HCC.