The results showed that compared with those in SALL4 mimic NC group, the protein expression levels of CyclinD, CyclinA1, PCNA and P62 in HepG2 and SMMC-7721 cells in SALL4 mimic group were significantly increased, suggesting that the overexpression of SALL4 can facilitate the proliferation and G1/S transition of tumor cells, and accelerate the cell cycle progression of HepG2 and SMMC-7721 cells, and the results were shown in Figure 3A and 3B. Here, PCNA is linked to neoplasm.