We randomly collected fresh tumor biopsies from 45 patients as a pilot cohort including 8 LA, 21 LB/H2−, 4 LB/H2+, 2 H2+ (HER2-positive nonluminal), and 10 TNBC tumors (SI Appendix, Fig. S4A). The gene discussed is ERBB2; the disease is neoplasm.