GLI4 and glioblastoma: Similar analysis, conducted on CD133+ glioblastoma stem cells (namely, Gli4 and Gli7) (Guichet et al, 2013) and patient‐derived glioblastoma stem‐like cells (GSC4, 6, 9, 13, 15) (Harford‐Wright et al, 2017), confirmed the absence of cGAS (Figs 1C and EV1B–D) and showed that upon challenge with dsDNA these cells present increased pIRF3 (Figs 1C and EV1B and D), IFNB and CXCL10 (Figs 1D and EV1E and F).