KDR and neoplasm: Despite both studies using sunitinib as a comparator, IMmotion AngioHigh and JAVELIN Angio had limited overlap with published GESs: only CD34 and KDR are present in both the JAVELIN Renal 101 Angio and the IMmotion150 angiogenesis GES, and only ECSCR, KDR, PTPRB, and TEK are present in both the JAVELIN Renal 101 Angio and an angiogenesis core signature identified in multiple tumor types [15], [17], [28].