Poor OS occurred with high PAQR4 expression in 11 tumor types (LGG (brain lower grade glioma), LUAD, KIRP, KIPAN (pankidney cohort), LIHC, BLCA, SKCM-M (skin cutaneous melanoma-metastasis), MESO, PAAD, LAML (acute myeloid leukemia), and ALL (acute lymphoblastic leukemia)) (Figure 4(a)). Here, PAQR4 is linked to central nervous system cancer.