Interestingly, the correlation coefficients were positive and statistically significant for all exposures with the strongest correlations for inflammation (IL10KO/SPF, r = 0.46, p < 0.0001) followed by microbiota (r = 0.39, p < 0.0001), AOM exposure (r = 0.36, p < 0.0001), and IL10 deficiency (r = 0.09, p < 0.0001). Here, IL10 is linked to infectious otitis media.