ECT2 manifested remarkably high transcriptional level in poorly differentiated tumor (Pooled OR = 3.95, 95%CI 3.40–4.59) (Fig. 3A) but low transcriptional level in ER + (Pooled OR = 0.45, 95%CI 0.39–0.53) (Fig. 3B) and PR + (Pooled OR = 0.52, 95%CI 0.42–0.64) patients (Fig. 3C). The gene discussed is ECT2; the disease is neoplasm.