In turn, estrogenic hypomethylated Alu sequences in the CMA3+ fraction of infertile patients were associated with an enrichment of genes involved in the internal male genital organs (BTO:0003096), the testis (BTO:0001363) and the male reproductive gland (BTO:0000080), including the CATSPERG gene. This evidence concerns the gene CATSPERG and Infertility.