GLP1R and atrial fibrillation: Regarding the association of AF risk and different GLP-1 RAs agents, dulaglutide displayed an increasing trend toward incident AF (RR 1.40, 95% CI 1.03–1.90; P = 0.03), while oral semaglutide displayed an inverse trend (RR 0.43, 95% CI 0.21–0.87; P = 0.02) (Fig. 3a).