APOE and dementia: Despite the fact that ApoE can act as an acceptor of cellular lipid efflux, we found no correlation of CSF CEC with CSF ApoE; we did, however, note a significant positive correlation between CSF ApoE and CSF Aβ1-42. In a previous study, the concentration of CSF ApoE was not associated with Aβ1-42 or clinical dementia diagnosis [44].