Therefore, we analyzed the expression level of CENPL mRNA in skin cutaneous melanoma (SKCM), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSC), kidney renal clear cell carcinoma (KIRC), breast invasive carcinoma (BRCA), and bladder urothelial carcinoma (BLCA) by GEPIA [17], for which immunotherapy have been approved. This evidence concerns the gene CENPL and invasive breast carcinoma.