Additionally, we previously reported mutations in spliceosome-related genes in 14.6% and 8.0%, respectively, of adult- and pediatric R/PR AML cases, including mutations in SF3B1/3, SRSF1/2/6, U2AF1 and ZRSR2 (ref. [19]). The gene discussed is SRSF1; the disease is acute myeloid leukemia.