NFKB1 and COVID-19: This observation suggests that other additional mechanisms may be regulating the activation of NFκB, and that NFκB-driven cytokine responses may be altered in patients with COVID-19, in agreement with the lack of increased pro-inflammatory cytokine expression by COVID-19 monocytes (Fig. 2c, Dataset 4) and with previous single cell transcriptomic data of acute COVID-19 PBMC29.