MUC1 and EMA lined the stroma-facing surfaces of the cell membranes, indicating reversed polarity.<h4>Conclusion</h4>Our current patient, who had an invasive breast carcinoma with concomitant neuroendocrine and micropapillary features, developed multiple nodal metastases in association with a large-diameter tumor showing a luminal B-like immuno-profile. Here, MUC1 is linked to neoplasm.