We found that p90ATF6 was significantly upregulated at MOI 2, MOI 5 and MOI 10 upon MHV-A59 infection for 24 h in mouse primary astrocytes compared to mock infected astrocytes (Fig. 1, K and L).These data demonstrate that there was a decrease in ERp29 concomitant with increased ER stress in response to MHV-A59 infection. This evidence concerns the gene ERP29 and infection.