Fourthly, the assessment, in this present study, of the range of microbial presence in different brain areas in AD and PD compared with control, needs to be considered in the knowledge of the known roles of Aβ and α-synuclein as antimicrobial peptides (AMPs) and their ability to escalate neuroinflammation in the presence of microbes. Here, ADSL is linked to Alzheimer disease.