Reportedly, IL-7 activates the JAK/STAT, PI3K/Akt, and mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK; MEK) pathways in normal T cells and T-cell acute lymphoblastic leukemia cells (33, 62–64). The gene discussed is SOAT1; the disease is T-cell acute lymphoblastic leukemia.