ICAM1 and Schnyder corneal dystrophy: The role of these cellular adhesion molecules [such as Intercellular Adhesion Molecule 1 (ICAM-1), P- and E-selectins and vascular cell adhesion molecule 1 (VCAM-1)] and thus endothelial activation in VOEs is further supported by a recent report of higher levels of E-selectin, VCAM-1, and ICAM-1 in SCD patients compared to controls (18).