ALCAM and lobular neoplasia: This was demonstrated in a study of 256 patients (ALN, active non-renal LN (ANR), inactive LN, inactive SLE) in a controlled cross-sectional study showing urine ALCAM (uALCAM) could be a strong biomarker for predicting renal histologic activity in LN and may serve as a valuable surrogate marker of renal histopathology (13).