Importantly, urine ALCAM LFA had the capacity to distinguish ALN patients from healthy subjects with high accuracy (ROC AUC=0.93, solid red line) and from all other lupus patients (ROC AUC=0.86, dashed red line), and were very comparable to the performance of the conventional ELISA assay (Figure 4F). The gene discussed is ALCAM; the disease is systemic lupus erythematosus.