TP53 and urinary bladder cancer: We found that bladder cancers of subtype BIS1 were mainly enriched in TP53-like and MS2b1 subtypes, samples of subtype BIS2 were mainly enriched in Basal and MS2b2, those with subtype BIS3 were primarily enriched in Luminal, MS1b and MS2a1 subtypes (Figure 4E).