We found that bladder cancers of subtype BIS1 were mainly enriched in TP53-like and MS2b1 subtypes, samples of subtype BIS2 were mainly enriched in Basal and MS2b2, those with subtype BIS3 were primarily enriched in Luminal, MS1b and MS2a1 subtypes (Figure 4E). Here, TP53 is linked to urinary bladder carcinoma.