The results showed that CAFs in P-LNs were associated with the high expression of NFIB, IGLC2, IGHG4, C7, and CCL19, while CAFs in tumor 3 had high expression of DIO2, LGALS1, WNT5A, NEAT1, and MMP11 in the tumor (Figure 5F; Supplementary Table S1). Here, IGHG4 is linked to neoplasm.