Twenty-one days post injury (dpi), brain tissue was collected and revealed comparable stroke volumes and a near complete overlap (> 99%) of affected brain areas in mice from all groups (WT = 2.8 ± 0.7 mm; WT-Tacr = 2.7 ± 0.7 mm3; Rag2-/- = 2.6 ± 0.4 mm3; NSG = 2.4 ± 0.3 mm3, all p = 1, Figures 1D, E; Supplementary Figure 1). This evidence concerns the gene RAG2 and stroke disorder.