IL21 and infection: We also observed a notable but non-significant increase in infection of germinal center cells (Figure 1E, top) In this analysis, the effect of IL-21 on infection within plasma cells was very consistent with increased targeting observed in nearly every sample, while in GC and plasmablasts there was a clear demarcation of samples that were either responsive or non-responsive to IL-21 supplementation (Figure 1E, bottom).