Blimp1 in Treg cells affects the growth rate of tumours dependent on the expression of Eomesodermin (Eomes), and causes changes in CD45 cells’ type I interferon in TME, resulting in the changes of the downstream angiogenic related genes, MHC I and MHC II molecules, and antigens, thereby altering the activity of tumour immune cells and immunogenicity of the tumour (24). The gene discussed is EOMES; the disease is neoplasm.